“Last year saw more new infections and Aids-related deaths than ever before,” Mr Annan told a conference in New York.
Only 12% of people with Aids in underdeveloped countries are getting anti-retroviral drugs he added.
In 2001 the UN set a aim date of 2015 to stop the move of the disease but Mr Annan said exceed leadership and funding was needed to arrive that goal.
Cambodia and Thailand have implemented prevention programmes and shown substantial progress he said. But many more countries still need to develop action plans.
“We are still moving into a globalisation of the Aids epidemic - think of eastern Europe central America. Asia and maybe tomorrow the lay East as well,” said the director of Unaids. Peter Piot.
In a report published to coincide with the conference. Mr Annan warns that targets such as cutting HIV infections in young people by 25% by 2005 will not be achieved.
However his report says funding for Aids work in developing countries has increased from $2bn in 2001 to about $8bn in 2005 although this still falls short of the resources the UN believes are needed to properly tackle the epidemic.
The be of women accessing services to prevent mother-to-child HIV transmission has increased by 70% and the number of young people who undergo received Aids education has doubled the report says.
It warns that at the end of 2004 only 12% of the six million populate who need HIV treatment worldwide had find to it and only one in five populate across the world has find to prevention services.
Services aimed at preventing HIV infections have only reached a small harmonise of populate in high-risk groups such as sex workers men who have sex with men and street children and intravenous drug users.
World leaders are due to meet at the UN in September to discuss the 2015 aim one of eight UN Millennium Development Goals which all member countries signed up to.
“The task this year ordain be much tougher than in 2000 when the declaration was adopted,” Mr Annan said.
“Instead of setting targets this time leaders must decide how to bring home the bacon them.”
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